Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nepsilon-acetyl-L-lysine - Names and Identifiers
Name | Fmoc-N'-Acetyl-L-lysine
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Synonyms | FMOC-LYS(AC)-OH FMOC-LYSINE(AC)-OH Fmoc-N'-Acetyl-L-lysine Fmoc-Lys(Ac)-OH Novabiochem FMOC-N-EPSILON-ACETYL-L-LYSINE Nepsilon-Acetyl-Nalpha-Fmoc-L-lysine N-ALPHA-FMOC-N-EPSILON-ACETYL-L-LYSINE Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nε-acetyl-L-lysine N~6~-acetyl-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-EPSILON-ACETYL-L-LYSINE Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nepsilon-acetyl-L-lysine
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CAS | 159766-56-0
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InChI | InChI=1/C23H26N2O5/c1-15(26)24-13-7-6-12-21(22(27)28)25-23(29)30-14-20-18-10-4-2-8-16(18)17-9-3-5-11-19(17)20/h2-5,8-11,20-21H,6-7,12-14H2,1H3,(H,24,26)(H,25,29)(H,27,28)/t21-/m0/s1 |
Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nepsilon-acetyl-L-lysine - Physico-chemical Properties
Molecular Formula | C23H26N2O5
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Molar Mass | 410.46 |
Density | 1.239±0.06 g/cm3(Predicted) |
Melting Point | 162.0 to 166.0 °C |
Boling Point | 709.4±60.0 °C(Predicted) |
Flash Point | 382.8°C |
Vapor Presure | 4.05E-21mmHg at 25°C |
pKa | 3.88±0.21(Predicted) |
Storage Condition | Store below +30°C. |
Refractive Index | 1.583 |
Physical and Chemical Properties | Storage Conditions:-15 ℃ |
Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nepsilon-acetyl-L-lysine - Risk and Safety
WGK Germany | WGK 2 water endanger |
HS Code | 2924 29 70 |
Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nepsilon-acetyl-L-lysine - Introduction
Fmoc-N '-Acetyl-L-lysine is a compound that has the following properties:
-Appearance: Usually white or off-white crystalline powder.
-Solubility: Soluble in organic solvents such as dichloromethane, dimethylformamide and diacetone, insoluble in water.
-Stability: It is quite stable under dry conditions, but may decompose in a humid environment.
Fmoc-N '-Acetyl-L-lysine are mainly used for the synthesis of peptides and proteins. It is commonly used as a protecting group in peptide synthesis and can protect the amine group in lysine. By introducing the Fmoc group, the amine group of lysine can be temporarily protected during the synthesis process to avoid side reactions with other reactants, and the protecting group can be removed when needed.
Fmoc-N '-Acetyl-L-lysine are generally prepared by chemical synthesis. Specific steps include reacting acetyl chloride with L-lysine to give acetylated lysine, which is then reacted with Fmoc-Cl to give Fmoc-N '-Acetyl-L-lysine.
For safety information, Fmoc-N '-Acetyl-L-lysine are chemicals that need to be stored and handled properly. When operating, follow safety laboratory specifications and wear personal protective equipment such as lab gloves and glasses. Avoid inhalation, ingestion or contact with skin. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. In addition, avoid reaction with strong oxidants or strong acids, and avoid storage in high temperature or humid environments. Detailed safety information can be found in the relevant chemical safety data sheets.
Last Update:2024-04-09 20:52:54